diff --git a/compiler/ir/backend.jvm/src/org/jetbrains/kotlin/backend/jvm/lower/inlineclasses/MemoizedInlineClassReplacements.kt b/compiler/ir/backend.jvm/src/org/jetbrains/kotlin/backend/jvm/lower/inlineclasses/MemoizedInlineClassReplacements.kt
index d59bdc02045..f5c4e2bdc88 100644
--- a/compiler/ir/backend.jvm/src/org/jetbrains/kotlin/backend/jvm/lower/inlineclasses/MemoizedInlineClassReplacements.kt
+++ b/compiler/ir/backend.jvm/src/org/jetbrains/kotlin/backend/jvm/lower/inlineclasses/MemoizedInlineClassReplacements.kt
@@ -51,7 +51,7 @@ class MemoizedInlineClassReplacements {
                         it.isSyntheticInlineClassMember ||
                         it.origin == IrDeclarationOrigin.LOCAL_FUNCTION_FOR_LAMBDA ||
                         it.origin == IrDeclarationOrigin.DELEGATED_PROPERTY_ACCESSOR ||
-                        it.origin == JvmLoweredDeclarationOrigin.POLYMORPHIC_SIGNATURE_INSTANTIATION -> null
+                        it.origin.isSynthetic -> null
                 it.hasMethodReplacement -> createMethodReplacement(it)
                 it.hasStaticReplacement -> createStaticReplacement(it)
                 else -> null
diff --git a/compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt b/compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt
new file mode 100644
index 00000000000..c1d7560f239
--- /dev/null
+++ b/compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt
@@ -0,0 +1,17 @@
+// IGNORE_BACKEND_FIR: JVM_IR
+
+@Target(AnnotationTarget.PROPERTY)
+annotation class Anno
+
+inline class Z(val s: String)
+
+class A {
+    @Anno
+    val Z.r: String get() = s
+}
+
+fun box(): String {
+    with(A()) {
+        return Z("OK").r
+    }
+}
diff --git a/compiler/tests/org/jetbrains/kotlin/codegen/BlackBoxCodegenTestGenerated.java b/compiler/tests/org/jetbrains/kotlin/codegen/BlackBoxCodegenTestGenerated.java
index 50e39d499fb..f1d7a5ae50d 100644
--- a/compiler/tests/org/jetbrains/kotlin/codegen/BlackBoxCodegenTestGenerated.java
+++ b/compiler/tests/org/jetbrains/kotlin/codegen/BlackBoxCodegenTestGenerated.java
@@ -12408,6 +12408,11 @@ public class BlackBoxCodegenTestGenerated extends AbstractBlackBoxCodegenTest {
             KotlinTestUtils.assertAllTestsPresentByMetadata(this.getClass(), new File("compiler/testData/codegen/box/inlineClasses"), Pattern.compile("^(.+)\\.kt$"), TargetBackend.JVM, true);
         }
 
+        @TestMetadata("annotatedMemberExtensionProperty.kt")
+        public void testAnnotatedMemberExtensionProperty() throws Exception {
+            runTest("compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt");
+        }
+
         @TestMetadata("boundCallableReferencePassedToInlineFunction.kt")
         public void testBoundCallableReferencePassedToInlineFunction() throws Exception {
             runTest("compiler/testData/codegen/box/inlineClasses/boundCallableReferencePassedToInlineFunction.kt");
diff --git a/compiler/tests/org/jetbrains/kotlin/codegen/LightAnalysisModeTestGenerated.java b/compiler/tests/org/jetbrains/kotlin/codegen/LightAnalysisModeTestGenerated.java
index c55f75b70fc..1e6f7eb15ad 100644
--- a/compiler/tests/org/jetbrains/kotlin/codegen/LightAnalysisModeTestGenerated.java
+++ b/compiler/tests/org/jetbrains/kotlin/codegen/LightAnalysisModeTestGenerated.java
@@ -12423,6 +12423,11 @@ public class LightAnalysisModeTestGenerated extends AbstractLightAnalysisModeTes
             KotlinTestUtils.assertAllTestsPresentByMetadata(this.getClass(), new File("compiler/testData/codegen/box/inlineClasses"), Pattern.compile("^(.+)\\.kt$"), TargetBackend.JVM, true);
         }
 
+        @TestMetadata("annotatedMemberExtensionProperty.kt")
+        public void testAnnotatedMemberExtensionProperty() throws Exception {
+            runTest("compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt");
+        }
+
         @TestMetadata("boundCallableReferencePassedToInlineFunction.kt")
         public void testBoundCallableReferencePassedToInlineFunction() throws Exception {
             runTest("compiler/testData/codegen/box/inlineClasses/boundCallableReferencePassedToInlineFunction.kt");
diff --git a/compiler/tests/org/jetbrains/kotlin/codegen/ir/FirBlackBoxCodegenTestGenerated.java b/compiler/tests/org/jetbrains/kotlin/codegen/ir/FirBlackBoxCodegenTestGenerated.java
index 4f8a327f81c..30bc5ac2d9d 100644
--- a/compiler/tests/org/jetbrains/kotlin/codegen/ir/FirBlackBoxCodegenTestGenerated.java
+++ b/compiler/tests/org/jetbrains/kotlin/codegen/ir/FirBlackBoxCodegenTestGenerated.java
@@ -11258,6 +11258,11 @@ public class FirBlackBoxCodegenTestGenerated extends AbstractFirBlackBoxCodegenT
             KotlinTestUtils.assertAllTestsPresentByMetadata(this.getClass(), new File("compiler/testData/codegen/box/inlineClasses"), Pattern.compile("^(.+)\\.kt$"), TargetBackend.JVM_IR, true);
         }
 
+        @TestMetadata("annotatedMemberExtensionProperty.kt")
+        public void testAnnotatedMemberExtensionProperty() throws Exception {
+            runTest("compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt");
+        }
+
         @TestMetadata("boundCallableReferencePassedToInlineFunction.kt")
         public void testBoundCallableReferencePassedToInlineFunction() throws Exception {
             runTest("compiler/testData/codegen/box/inlineClasses/boundCallableReferencePassedToInlineFunction.kt");
diff --git a/compiler/tests/org/jetbrains/kotlin/codegen/ir/IrBlackBoxCodegenTestGenerated.java b/compiler/tests/org/jetbrains/kotlin/codegen/ir/IrBlackBoxCodegenTestGenerated.java
index 5fc054492a8..5a54c2d607e 100644
--- a/compiler/tests/org/jetbrains/kotlin/codegen/ir/IrBlackBoxCodegenTestGenerated.java
+++ b/compiler/tests/org/jetbrains/kotlin/codegen/ir/IrBlackBoxCodegenTestGenerated.java
@@ -11258,6 +11258,11 @@ public class IrBlackBoxCodegenTestGenerated extends AbstractIrBlackBoxCodegenTes
             KotlinTestUtils.assertAllTestsPresentByMetadata(this.getClass(), new File("compiler/testData/codegen/box/inlineClasses"), Pattern.compile("^(.+)\\.kt$"), TargetBackend.JVM_IR, true);
         }
 
+        @TestMetadata("annotatedMemberExtensionProperty.kt")
+        public void testAnnotatedMemberExtensionProperty() throws Exception {
+            runTest("compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt");
+        }
+
         @TestMetadata("boundCallableReferencePassedToInlineFunction.kt")
         public void testBoundCallableReferencePassedToInlineFunction() throws Exception {
             runTest("compiler/testData/codegen/box/inlineClasses/boundCallableReferencePassedToInlineFunction.kt");
diff --git a/js/js.tests/test/org/jetbrains/kotlin/js/test/ir/semantics/IrJsCodegenBoxTestGenerated.java b/js/js.tests/test/org/jetbrains/kotlin/js/test/ir/semantics/IrJsCodegenBoxTestGenerated.java
index 52efe99975b..01905aeb07b 100644
--- a/js/js.tests/test/org/jetbrains/kotlin/js/test/ir/semantics/IrJsCodegenBoxTestGenerated.java
+++ b/js/js.tests/test/org/jetbrains/kotlin/js/test/ir/semantics/IrJsCodegenBoxTestGenerated.java
@@ -9743,6 +9743,11 @@ public class IrJsCodegenBoxTestGenerated extends AbstractIrJsCodegenBoxTest {
             KotlinTestUtils.assertAllTestsPresentByMetadata(this.getClass(), new File("compiler/testData/codegen/box/inlineClasses"), Pattern.compile("^(.+)\\.kt$"), TargetBackend.JS_IR, true);
         }
 
+        @TestMetadata("annotatedMemberExtensionProperty.kt")
+        public void testAnnotatedMemberExtensionProperty() throws Exception {
+            runTest("compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt");
+        }
+
         @TestMetadata("boundCallableReferencePassedToInlineFunction.kt")
         public void testBoundCallableReferencePassedToInlineFunction() throws Exception {
             runTest("compiler/testData/codegen/box/inlineClasses/boundCallableReferencePassedToInlineFunction.kt");
diff --git a/js/js.tests/test/org/jetbrains/kotlin/js/test/semantics/JsCodegenBoxTestGenerated.java b/js/js.tests/test/org/jetbrains/kotlin/js/test/semantics/JsCodegenBoxTestGenerated.java
index d963764e19f..b1a1f3387e1 100644
--- a/js/js.tests/test/org/jetbrains/kotlin/js/test/semantics/JsCodegenBoxTestGenerated.java
+++ b/js/js.tests/test/org/jetbrains/kotlin/js/test/semantics/JsCodegenBoxTestGenerated.java
@@ -10883,6 +10883,11 @@ public class JsCodegenBoxTestGenerated extends AbstractJsCodegenBoxTest {
             KotlinTestUtils.assertAllTestsPresentByMetadata(this.getClass(), new File("compiler/testData/codegen/box/inlineClasses"), Pattern.compile("^(.+)\\.kt$"), TargetBackend.JS, true);
         }
 
+        @TestMetadata("annotatedMemberExtensionProperty.kt")
+        public void testAnnotatedMemberExtensionProperty() throws Exception {
+            runTest("compiler/testData/codegen/box/inlineClasses/annotatedMemberExtensionProperty.kt");
+        }
+
         @TestMetadata("boundCallableReferencePassedToInlineFunction.kt")
         public void testBoundCallableReferencePassedToInlineFunction() throws Exception {
             runTest("compiler/testData/codegen/box/inlineClasses/boundCallableReferencePassedToInlineFunction.kt");