diff --git a/kotlin-native/Interop/StubGenerator/src/main/kotlin/org/jetbrains/kotlin/native/interop/gen/Imports.kt b/kotlin-native/Interop/StubGenerator/src/main/kotlin/org/jetbrains/kotlin/native/interop/gen/Imports.kt
index a3f65856d15..f15f2ed3cb6 100644
--- a/kotlin-native/Interop/StubGenerator/src/main/kotlin/org/jetbrains/kotlin/native/interop/gen/Imports.kt
+++ b/kotlin-native/Interop/StubGenerator/src/main/kotlin/org/jetbrains/kotlin/native/interop/gen/Imports.kt
@@ -41,10 +41,14 @@ class ImportsImpl(internal val headerIdToPackage: Map<HeaderId, PackageInfo>) :
         get() = accessedLibraries.toSet()
 }
 
-class HeaderInclusionPolicyImpl(private val nameGlobs: List<String>) : HeaderInclusionPolicy {
+class HeaderInclusionPolicyImpl(
+        private val nameGlobs: List<String>,
+        private val excludeGlobs: List<String>,
+) : HeaderInclusionPolicy {
 
     override fun excludeUnused(headerName: String?): Boolean {
-        if (nameGlobs.isEmpty()) {
+        // If we don't have any filters then we should keep the header.
+        if (nameGlobs.isEmpty() && excludeGlobs.isEmpty()) {
             return false
         }
 
@@ -53,7 +57,8 @@ class HeaderInclusionPolicyImpl(private val nameGlobs: List<String>) : HeaderInc
             return true
         }
 
-        return nameGlobs.all { !headerName.matchesToGlob(it) }
+        // Exclude globs have higher priority then include ones.
+        return excludeGlobs.any { headerName.matchesToGlob(it) } || nameGlobs.all { !headerName.matchesToGlob(it) }
     }
 }
 
diff --git a/kotlin-native/Interop/StubGenerator/src/main/kotlin/org/jetbrains/kotlin/native/interop/gen/jvm/main.kt b/kotlin-native/Interop/StubGenerator/src/main/kotlin/org/jetbrains/kotlin/native/interop/gen/jvm/main.kt
index ae7755cb2f6..3a19b6ab429 100644
--- a/kotlin-native/Interop/StubGenerator/src/main/kotlin/org/jetbrains/kotlin/native/interop/gen/jvm/main.kt
+++ b/kotlin-native/Interop/StubGenerator/src/main/kotlin/org/jetbrains/kotlin/native/interop/gen/jvm/main.kt
@@ -160,12 +160,13 @@ fun getCompilerFlagsForVfsOverlay(headerFilterPrefix: Array<String>, def: DefFil
     val filteredIncludeDirs = headerFilterPrefix .map { Paths.get(it) }
     if (filteredIncludeDirs.isNotEmpty()) {
         val headerFilterGlobs = def.config.headerFilter
+        val excludeFilterGlobs = def.config.excludeFilter
         if (headerFilterGlobs.isEmpty()) {
             error("'$HEADER_FILTER_ADDITIONAL_SEARCH_PREFIX' option requires " +
                     "'headerFilter' to be specified in .def file")
         }
 
-        relativeToRoot += findFilesByGlobs(roots = filteredIncludeDirs, globs = headerFilterGlobs)
+        relativeToRoot += findFilesByGlobs(roots = filteredIncludeDirs, includeGlobs = headerFilterGlobs, excludeGlobs = excludeFilterGlobs)
     }
 
     if (relativeToRoot.isEmpty()) {
@@ -183,10 +184,11 @@ fun getCompilerFlagsForVfsOverlay(headerFilterPrefix: Array<String>, def: DefFil
     return listOf("-I${virtualRoot.toAbsolutePath()}", "-ivfsoverlay", vfsOverlayFile.toAbsolutePath().toString())
 }
 
-private fun findFilesByGlobs(roots: List<Path>, globs: List<String>): Map<Path, Path> {
+private fun findFilesByGlobs(roots: List<Path>, includeGlobs: List<String>, excludeGlobs: List<String>): Map<Path, Path> {
     val relativeToRoot = mutableMapOf<Path, Path>()
 
-    val pathMatchers = globs.map { FileSystems.getDefault().getPathMatcher("glob:$it") }
+    val pathMatchers = includeGlobs.map { FileSystems.getDefault().getPathMatcher("glob:$it") }
+    val excludePathMatchers = excludeGlobs.map { FileSystems.getDefault().getPathMatcher("glob:$it") }
 
     roots.reversed()
             .filter { path ->
@@ -199,7 +201,10 @@ private fun findFilesByGlobs(roots: List<Path>, globs: List<String>): Map<Path,
                 // TODO: don't scan the entire tree, skip subdirectories according to globs.
                 Files.walk(root, FileVisitOption.FOLLOW_LINKS).forEach { path ->
                     val relativePath = root.relativize(path)
-                    if (!Files.isDirectory(path) && pathMatchers.any { it.matches(relativePath) }) {
+                    val shouldInclude = !Files.isDirectory(path)
+                            && excludePathMatchers.all { !it.matches(relativePath) }
+                            && pathMatchers.any { it.matches(relativePath) }
+                    if (shouldInclude) {
                         relativeToRoot[relativePath] = root
                     }
                 }
@@ -504,7 +509,8 @@ internal fun buildNativeLibrary(
         val excludeDependentModules = def.config.excludeDependentModules
 
         val headerFilterGlobs = def.config.headerFilter
-        val headerInclusionPolicy = HeaderInclusionPolicyImpl(headerFilterGlobs)
+        val excludeFilterGlobs = def.config.excludeFilter
+        val headerInclusionPolicy = HeaderInclusionPolicyImpl(headerFilterGlobs, excludeFilterGlobs)
 
         headerFilter = NativeLibraryHeaderFilter.NameBased(headerInclusionPolicy, excludeDependentModules)
         includes = headerFiles
diff --git a/kotlin-native/shared/src/main/kotlin/org/jetbrains/kotlin/konan/util/DefFile.kt b/kotlin-native/shared/src/main/kotlin/org/jetbrains/kotlin/konan/util/DefFile.kt
index 5bca0601399..00a5004745d 100644
--- a/kotlin-native/shared/src/main/kotlin/org/jetbrains/kotlin/konan/util/DefFile.kt
+++ b/kotlin-native/shared/src/main/kotlin/org/jetbrains/kotlin/konan/util/DefFile.kt
@@ -86,10 +86,20 @@ class DefFile(val file:File?, val config:DefFileConfig, val manifestAddendProper
             properties.getProperty("package")
         }
 
+        /**
+         * Header inclusion globs.
+         */
         val headerFilter by lazy {
             properties.getSpaceSeparated("headerFilter")
         }
 
+        /**
+         * Header exclusion globs. Have higher priority than [headerFilter].
+         */
+        val excludeFilter by lazy {
+            properties.getSpaceSeparated("excludeFilter")
+        }
+
         val strictEnums by lazy {
             properties.getSpaceSeparated("strictEnums")
         }