diff --git a/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/kotlin/org/jetbrains/kotlin/gradle/BaseGradleIT.kt b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/kotlin/org/jetbrains/kotlin/gradle/BaseGradleIT.kt
index c0c29c6893b..0af40117ac6 100644
--- a/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/kotlin/org/jetbrains/kotlin/gradle/BaseGradleIT.kt
+++ b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/kotlin/org/jetbrains/kotlin/gradle/BaseGradleIT.kt
@@ -294,7 +294,7 @@ abstract class BaseGradleIT {
         open val resourcesRoot = File(resourcesRootFile, "testProject/$resourceDirName")
         val projectDir = File(workingDir.canonicalFile, projectName)
 
-        open fun setupWorkingDir(enableCacheRedirector: Boolean = true) {
+        open fun setupWorkingDir(enableCacheRedirector: Boolean = true, applyAndroidTestFixes: Boolean = true) {
             if (!projectDir.isDirectory || projectDir.listFiles().isEmpty()) {
                 copyRecursively(this.resourcesRoot, workingDir)
                 if (addHeapDumpOptions) {
@@ -304,7 +304,7 @@ abstract class BaseGradleIT {
                 projectDir.toPath().apply {
                     addPluginManagementToSettings()
                     if (enableCacheRedirector) enableCacheRedirector()
-                    applyAndroidTestFixes()
+                    if (applyAndroidTestFixes) applyAndroidTestFixes()
                 }
             }
         }
diff --git a/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/kotlin/org/jetbrains/kotlin/gradle/CommonizerHierarchicalIT.kt b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/kotlin/org/jetbrains/kotlin/gradle/CommonizerHierarchicalIT.kt
index c13bcc11193..0d422a96798 100644
--- a/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/kotlin/org/jetbrains/kotlin/gradle/CommonizerHierarchicalIT.kt
+++ b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/kotlin/org/jetbrains/kotlin/gradle/CommonizerHierarchicalIT.kt
@@ -132,6 +132,17 @@ class CommonizerHierarchicalIT : BaseGradleIT() {
         }
     }
 
+    @Test
+    fun `test KT-50592 - isolated jvm subproject - should not fail commonization`() {
+        with(Project("commonize-kt-50592-withIsolatedJvmSubproject")) {
+            setupWorkingDir(applyAndroidTestFixes = false) // Necessary to ensure separated classpath
+            build("commonize") {
+                assertSuccessful()
+                assertTasksExecuted(":commonizeNativeDistribution")
+            }
+        }
+    }
+
     private object Os {
         private val os = OperatingSystem.current()
         val canCompileApple get() = os.isMacOsX
diff --git a/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/build.gradle.kts b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/build.gradle.kts
new file mode 100644
index 00000000000..5948671485a
--- /dev/null
+++ b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/build.gradle.kts
@@ -0,0 +1,6 @@
+allprojects {
+    repositories {
+        mavenLocal()
+        mavenCentral()
+    }
+}
diff --git a/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/jvm/build.gradle.kts b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/jvm/build.gradle.kts
new file mode 100644
index 00000000000..444baaa3c8c
--- /dev/null
+++ b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/jvm/build.gradle.kts
@@ -0,0 +1,3 @@
+plugins {
+    kotlin("jvm")
+}
diff --git a/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/multiplatform/build.gradle.kts b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/multiplatform/build.gradle.kts
new file mode 100644
index 00000000000..691c18166e6
--- /dev/null
+++ b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/multiplatform/build.gradle.kts
@@ -0,0 +1,17 @@
+plugins {
+    kotlin("multiplatform")
+}
+
+kotlin {
+    linuxArm64()
+    linuxX64()
+
+    val commonMain by sourceSets.getting
+    val linuxMain by sourceSets.creating
+    val linuxArm64Main by sourceSets.getting
+    val linuxX64Main by sourceSets.getting
+
+    linuxMain.dependsOn(commonMain)
+    linuxArm64Main.dependsOn(linuxMain)
+    linuxX64Main.dependsOn(linuxMain)
+}
diff --git a/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/settings.gradle.kts b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/settings.gradle.kts
new file mode 100644
index 00000000000..f8163ad242c
--- /dev/null
+++ b/libraries/tools/kotlin-gradle-plugin-integration-tests/src/test/resources/testProject/commonize-kt-50592-withIsolatedJvmSubproject/settings.gradle.kts
@@ -0,0 +1,2 @@
+include("jvm")
+include("multiplatform")