diff --git a/js/js.inliner/src/org/jetbrains/kotlin/js/inline/clean/RedundantStatementElimination.kt b/js/js.inliner/src/org/jetbrains/kotlin/js/inline/clean/RedundantStatementElimination.kt
index 57c01c39e06..2650583f0a0 100644
--- a/js/js.inliner/src/org/jetbrains/kotlin/js/inline/clean/RedundantStatementElimination.kt
+++ b/js/js.inliner/src/org/jetbrains/kotlin/js/inline/clean/RedundantStatementElimination.kt
@@ -36,12 +36,26 @@ class RedundantStatementElimination(private val root: JsFunction) {
     private fun process() {
         object : JsVisitorWithContextImpl() {
             override fun visit(x: JsExpressionStatement, ctx: JsContext<JsNode>): Boolean {
-                if (!x.expression.isSuspend && (x.synthetic || x.expression.synthetic)) {
-                    val replacement = replace(x.expression)
-                    if (replacement.size != 1 || replacement[0] != x.expression) {
-                        hasChanges = true
-                        ctx.addPrevious(replacement.map { JsExpressionStatement(it).apply { synthetic = true } })
-                        ctx.removeMe()
+                if (!x.expression.isSuspend) {
+                    val expression = x.expression
+                    if (x.synthetic || expression.synthetic) {
+                        val replacement = replace(x.expression)
+                        if (replacement.size != 1 || replacement[0] != x.expression) {
+                            hasChanges = true
+                            ctx.addPrevious(replacement.map { JsExpressionStatement(it).apply { synthetic = true } })
+                            ctx.removeMe()
+                        }
+                    }
+                    else if (expression is JsBinaryOperation && expression.operator == JsBinaryOperator.COMMA) {
+                        var currentExpression = expression
+                        while (currentExpression is JsBinaryOperation && currentExpression.operator == JsBinaryOperator.COMMA) {
+                            val replacement = replace(currentExpression.arg2)
+                            if (replacement.isNotEmpty()) break
+                            currentExpression = currentExpression.arg1
+                        }
+                        if (currentExpression != expression) {
+                            ctx.replaceMe(JsExpressionStatement(currentExpression).apply { copyMetadataFrom(x) })
+                        }
                     }
                 }
                 return super.visit(x, ctx)