diff --git a/libraries/tools/kotlin-gradle-plugin/src/common/kotlin/org/jetbrains/kotlin/gradle/targets/native/internal/CInteropMetadataDependencyTransformationTask.kt b/libraries/tools/kotlin-gradle-plugin/src/common/kotlin/org/jetbrains/kotlin/gradle/targets/native/internal/CInteropMetadataDependencyTransformationTask.kt
index 4b5477a847d..1eb7d2c6736 100644
--- a/libraries/tools/kotlin-gradle-plugin/src/common/kotlin/org/jetbrains/kotlin/gradle/targets/native/internal/CInteropMetadataDependencyTransformationTask.kt
+++ b/libraries/tools/kotlin-gradle-plugin/src/common/kotlin/org/jetbrains/kotlin/gradle/targets/native/internal/CInteropMetadataDependencyTransformationTask.kt
@@ -29,6 +29,7 @@ import org.jetbrains.kotlin.gradle.tasks.locateOrRegisterTask
 import org.jetbrains.kotlin.gradle.tasks.withType
 import org.jetbrains.kotlin.gradle.utils.filesProvider
 import org.jetbrains.kotlin.gradle.utils.lowerCamelCaseName
+import org.jetbrains.kotlin.gradle.utils.notCompatibleWithConfigurationCache
 import org.jetbrains.kotlin.gradle.utils.outputFilesProvider
 import org.jetbrains.kotlin.library.KLIB_FILE_EXTENSION
 import org.jetbrains.kotlin.project.model.KpmModuleIdentifier
@@ -102,6 +103,10 @@ internal open class CInteropMetadataDependencyTransformationTask @Inject constru
     @get:OutputDirectory val outputDirectory: File
 ) : DefaultTask() {
 
+    init {
+        notCompatibleWithConfigurationCache("Task $name does not support Gradle Configuration Cache. Check KT-49933 for more info")
+    }
+
     @Suppress("unused")
     class ChooseVisibleSourceSetProjection(
         @Input val dependencyModuleIdentifiers: List<KpmModuleIdentifier>,